Le LBCM accueille deux jeunes chercheurs indonésiens

Le LBCM accueille deux jeunes chercheurs indonésiens de l'Université DiponegoroThe laboratory hosts for 6 months two PhD students in ERASMUS+ mobility from Diponegoro University in Indonesia. They are under the direction of the Prof. Ocky Karna Radjasa, Ph.D Director Directorate of Research and Community Services Ministry of Research Technology and Higher Education and Dr. Agus Sabdono.

Context

Indonesia as one of the mega diversity countries and the fact that 70% of Indonesia is covered by marine environment, therefore it is reasonable to exploit the less developed marine resources. There are a lot of organisms in the ocean, which have potency to be drugs. Marine invertebrate exploration has a significant impact on marine conservation in which it may threaten the richness of marine invertebrates.

Studying symbiont bacteria associated with marine invertebrates provides a lot of advantages that will not harm the precious coral reef ecosystem. Bacterial symbionts have received more attentions in the recent years as the new sources of marine bioactive molecules. Finding new compounds structure to serve, as an anti-MRSA agent is imperative. Recent studies have shown that marine organisms such as sponges, bryozoans, tunicates and gorgonians produce bioactive compounds, which have potency to be used as a source of medicine. More than 1000 new bioactive compounds have been identified in the bacteria carried by these marine invertebrates. Bioactive compounds from marine invertebrates have biological properties, which are essential in the development of new drugs.

Bacteria associated with marine invertebrate indicated having the same compound with its host; investigating the new structure from bacterial symbiont with Nudibranch and Bryozoan (marine invertebrate), which has activity to combat Methicillin Resistant S. aureus (MRSA) is important. Therefore it can be an alternative in the culture and synthetic drugs in the future.

Research program

The project of RhesiI Kristiana concerns Anti-MRSA (Methicillin-Resistant Staphylococcus aureus) Potential of Bacterial Symbionts of Nudibranchs from Indonesia.

The project of Meezan Ardhanu Asagabaldan propose to study the determination of bioactive compounds of bioactive componds from bacteria associated of marine Bryozoans against multidrug-resistant (MDR) bacteria.

During their stay, doctoral students work on the identification of the active iextracts of microbial extracts obtained from the marine invertebrates.